It has been reported that visual disorder may occur when carboxyhemoglobin
is 30-40% (14).
With a cutoff of 6% and higher for carboxyhemoglobin
, the sensitivity was 46% and the specificity was 94% to detect a smoker, with a positive predictive value of 67% and a negative predictive value of 87%, said Dr.
Broder said he was struck by "how some people with CO poisoning were relatively asymptomatic" and how patients with similar carboxyhemoglobin
levels "had such varying clinical presentations.
All presenting patients should have laboratory samples drawn, beginning with either an arterial or venous blood gas to determine the carboxyhemoglobin
(COHb) level, (12) although the COHb numerical value in itself does not necessarily correlate clinically.
The most characteristic sign of CO poisoning is a cherry color of the skin and mucous membranes due to the bright red color of carboxyhemoglobin
In 2005, Masimo introduced rainbow SET[R] Pulse CO-Oximetry[TM] technology, allowing noninvasive and continuous monitoring of blood constituents that previously required invasive procedures, including total hemoglobin (SpHb[R]), oxygen content (SpOC[TM]), carboxyhemoglobin
(SpCO[R]), methemoglobin (SpMet[R]), and Pleth Variability Index (PVI[R]), in addition to SpO2, pulse rate, and perfusion index (PI).
In conjunction with the appropriate Philips patient monitoring platform, Masimos rainbow SET technology analyzes multiple wavelengths of light to accurately measure total hemoglobin (SpHb), oxygen content (SpOC), carboxyhemoglobin
(SpCO), methemoglobin (SpMet) and Pleth Variability Index (PVI) non-invasively and continuously.
, exhaled CO, lymphocyte DNA damage, urinary 1-hydroxypyrene, or ST-segment depression) in the residents of the home (Eppler et al.
Once absorbed, the smoke creates methhemoglobin and carboxyhemoglobin
in the patient's blood.
11 parameters include: 1) oxygen saturation (SpO2); 2) Pulse rate; 3) Perfusion index (PI); 4) Pleth Variability Index (PVI); 5) Respiration Rate from the pleth (RRp); 6) Total hemoglobin (SpHb); 7) Oxygen Content (SpOC); 8) Carboxyhemoglobin
(SpCO); 9) Methemoglobin (SpMet); 10) Fractional oxygen saturation (SpfO2); 11) Oxygen Reserve Index (ORI)
Additionally, smoked cannabis is associated with an increase in carboxyhemoglobin
, resulting in decreased oxygen-carrying capacity (4-6).
In clinical chemistry, the hallmark of these protective systems is the unconjugated hyperbilirubinemia associated with hemolysis and even a mild/moderate increase of carboxyhemoglobin