Carboxyhemoglobin


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Related to Carboxyhemoglobin: methemoglobin, carbon monoxide poisoning, carboxyhemoglobin test

carboxyhemoglobin

[kär¦bäk·sē¦hē·mə‚glō·bən]
(biochemistry)

Carboxyhemoglobin

 

HbCO, a compound formed by the binding of carbon monoxide (CO) to hemoglobin (Hb).

Carboxyhemoglobin solutions are bright red. Their absorption spectrum has maximums at wavelengths of 570 and 539 mμ. Carboxyhemoglobin breaks down to Hb and CO 10, 000 times more slowly than does oxyhemoglobin to Hb and O2. Therefore, when CO is present in inhaled air the oxygen is gradually displaced from the hemoglobin. Even at an atmospheric CO concentration of 0.1 percent, more than half the hemoglobin in the blood is converted to carboxyhemoglobin, interfering with the transfer of O2 from the lungs to the tissues and causing carbonmonoxide poisoning.

References in periodicals archive ?
Significant differences were also found between nonsmokers' and secondhand smokers' mean carboxyhemoglobin (2.
Obtain a venous (preferably) or arterial (only if other associated respiratory findings are present) carboxyhemoglobin level on all patients with a history or suspicion of exposure, even if they are asymptomatic.
Also, the delay between exposure and blood sampling as well as oxygen therapy administered during this period can account for a significantly reduced carboxyhemoglobin level.
Rapid determination of carboxyhemoglobin in blood by oximeter.
Masimo Rainbow SET continuously and noninvasively measures total hemoglobin (SpHb(TM)), oxygen content (SpOC(TM)), carboxyhemoglobin (SpCO([R])), methemoglobin (SpMet([R])), and PVI(TM), in addition to oxyhemoglobin (SpO2), pulse rate (PR), and perfusion index (PI), allowing early detection and treatment of potentially life-threatening conditions.
In 2005, Masimo introduced rainbow SET Pulse CO-Oximetry™ technology, allowing noninvasive and continuous monitoring of blood constituents that previously required invasive procedures, including total hemoglobin (SpHb), oxygen content (SpOC™), carboxyhemoglobin (SpCO), methemoglobin (SpMet), and Pleth Variability Index (PVI), in addition to SpO2, pulse rate, and perfusion index (PI).
A common form of abnormal hemoglobin is carboxyhemoglobin (HbCO).
In view of the principle of operation used by the Hb-Quick, it is understandable that this hemoglobinometer was relatively unaffected by carboxyhemoglobin because it includes that species in its measurement of total hemoglobin.
Parameters at Saint Mary's include total hemoglobin (SpHb), and carboxyhemoglobin (SpCO), as well as the Measure-Through Motion and Low Perfusion performance of Masimo SET oxyhemoglobin (SpO[sub.
Masimo Rainbow SET continuously and noninvasively measures total hemoglobin (SpHb(TM)), oxygen content (SpOC(TM)), carboxyhemoglobin (SpCO(R)), methemoglobin (SpMet(R)), and PVI(TM), in addition to oxyhemoglobin (SpO2), pulse rate (PR), and perfusion index (PI), allowing early detection and treatment of potentially life-threatening conditions.
Our results on the Radiometer OSM3 (not shown) confirmed the reported effects (1) on oxyhemoglobin, carboxyhemoglobin, and methemoglobin.
Pulse CO-Oximetry (TM), which allows clinicians to noninvasively monitor multiple blood constituents that previously required invasive or complicated procedures, including total hemoglobin (SpHb), oxygen content (SpOC (TM)), carboxyhemoglobin (SpCO), methemoglobin (SpMet), Pleth Variability Index (PVI), and acoustic respiration rate (RRa (TM)).