Carboxylases


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Carboxylases

 

a group of enzymes of the lyase class, catalyzing decarboxylation (CO2 separation) of keto and aminoacids. Cocarboxylase acts as a coenzyme of carboxylases thatdecarboxylize keto acids, pyridoxal phosphate serves as a coen-zyme of carboxylases that catalyze the decarboxylation of aminoacids.

References in periodicals archive ?
In its physiologically active form, biotin is covalently attached to these carboxylases via an amide linkage to a specific lysine residue (4).
Biotin is a cofactor in metabolic reactions which require carboxylases.
Inhibition of several genes, such as stearoyl-CoA desaturase 1 (SCD-1), acetyl-CoA carboxylases 1 (ACC1) and diacylglycerol acyltransferase 2 (DGAT2) resulted in decreased fat synthesis, increased fat oxidation (burning) and a clearing of fat in the liver.
PEP carboxylase has been the subject of extensive experimental research in the last decades [1,2].