Effects of biotin on pyruvate carboxylase
, acetyl-CoA carboxylase
, propionyl-CoA carboxylase
, and markers for glucose and lipid homeostasis in type 2 diabetic patients and nondiabetic subjects.
In its physiologically active form, biotin is covalently attached to these carboxylases
via an amide linkage to a specific lysine residue (4).
To examine the biosynthetic pathway for Gla, we have studied the Conus carboxylase
which converts glutamic acid to [beta]-carboxyglutamic acid in the presence of vitamin K.
Comparison of the predicted amino acid sequences identified a highly conserved 32-amino acid residue region in all of these putative carboxylases
Key words: PCR-SSCP, goat, Acetyl coenzyme A carboxylase a, milk traits
Among enzymes involved in lipogenesis, acetyl- coenzyme A carboxylase a (ACACA) has been considered for its special regulatory role in fatty acid biosynthesis by catalyzing the ATP-dependent formation of malonyl-coenzyme A (Cronan and Waldrop, 2002; Badaoui et al.
PEP carboxylase has been the subject of extensive experimental research in the last decades [1,2].
Physical and kinetic properties of photosynthetic PEP carboxylase in developing apple fruit.
To what extent rubisco acts as carboxylase
or oxygenase depends upon the relative concentrations of [CO.