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(organic chemistry)
Addition of a carboxyl group into a molecule.



the direct introduction of the carboxyl group —COOH to organic compounds by the action of CO2. For example, carboxylation of organometallic compounds occurs during the passage of CO2 through a solution of the compound; subsequent hydrolysis yields carboxylic acid:

Salicylic acid and ^-aminosalicylic acid (PASA), used in medicine, are obtained through a singular carboxylation process involving the corresponding phenolates, for example

Carboxylation in an organism is effected by specific enzymes, forexample, pyruvate carboxylase catalyzes the carboxylation ofpyruvic acid. Carboxylation plays an important role in the oxida-tion of intermediate products of the decomposition of carbohy-drates, fats, and proteins in the organism.

References in periodicals archive ?
The cells lining the tips and the crypts of the glands of gizzard were covered by a layer of carboxylated mucins.
This research takes an important step towards the replacement of synthetic films with biodegradable films by improving the properties of gluten films by using carboxylated cellulose nanocrystals.
Increased levels of not completely carboxylated osteocalcin are linked to a decrease in BMD and thus to the development of osteoporosis.
Since the alkali-swelling of carboxylated latex particles (1-4) has been extensively studied by both industrial and academic scientists in the past, it has been well understood that their alkali-swelling increases with increasing acid content and hydrophilicity of backbone polymers and decreases with increasing [T.
In this pathway the naphthalene is carboxylated to 2-NA followed by a series of reduction steps where hydrogen is added to the unsubstituted ring first and then to the ring with the carboxyl group.
Parker Hannifin's Seal Group) is offering sealing products in carboxylated HNBR (XHNBR) a material that combines the temperature resistance of highly saturated nitrile (XNBR) with the durability of carboxylated nitrile (HNBR).
In addition, assay 9 is relatively specific to the carboxylated form of hOC.
The compatibilizing efficiency of this carboxylated PP is compared to that of maleic anhydride grafted PP.
The "GenFlo" product line features various chemistries that include carboxylated, non-carboxylated and carboxy-modified latices providing a wide range of hand properties from very soft to stiff.
Information is provided on the following products: Nipol nitrile elastomers; Nipol carboxylated nitrile elastomers; Nipol terpolymer elastomers; Nipol liquid nitrile elastomers; Nipol nitrile powder and crumb elastomers; Zealloy modifiers for thermoplastics; DuoMod tougheners; Nipol and Sivic polyblends and oilextended nitrile elastomers; Chemisat HNBR latex; Zetpol hydrogenated nitrile elastomers; Zetpol HP HNBR; Zetpol EP HNBR; Zetpol ZLX HNBR latex; Zeoforte modified hydrogenated nitrile elastomers; HyTemp polyacrylate elastomers; HyTemp high-performance polyacrylate elastomers; HyTemp polyacrylate curatives and additives; Hydrin polyepichlorohydrin elastomers, and more.
A low serum carboxylated osteocalcin level or high undercarboxylated osteocalcin level could be risk factors for femoral neck fracture.