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(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


References in periodicals archive ?
Third, an in-depth genetic analysis conducted in one of the dilated cardiomyopathy families with a member who had peripartum cardiomyopathy revealed a mutation in TNNC1, the gene encoding cardiac troponin C.
Postpartum cardiomyopathy associated with maternal cocaine abuse.
For the HS cTnT analysis related to cardiomyopathy severity, patients with mild and moderate cardiomyopathy were combined because of the low percentage of mild cardiomyopathy (10%) in our study cohort.
27) also has reported higher incidence rate of spontaneous events including death and worsening of clinical status with lower coronary flow reserve assessed by Doppler echocardiography in patients with non-ischemic dilated cardiomyopathy.
Arrhythmias, valvulopathy, and restrictive cardiomyopathy are common complications.
9,10) Hypertrophic cardiomyopathy may have also been responsible for syncope in our patient.
As well as becoming a ward volunteer at Glan Clwyd Hospital, earlier this year he attended a training day run by the Cardiomyopathy Association for volunteers who want to offer support to other sufferers on the telephone.
A review of all records for patients with discharge diagnoses of myocarditis or cardiomyopathy at all 5 hospitals in Kane County from October 1, 2002, through March 31, 2003, was conducted to find unreported cases of myocarditis.
com adds "Cardiomyopathy - Pipeline Review, H2 2015" therapeutics research report of 119 pages, talking about 16 companies and multiple cardiomyopathy drug profiles to its online library.
Takotsubo cardiomyopathy is characterized by transient left ventricular dysfunction with chest symptoms, elevated cardiac enzymes, and electrocardiographic changes such as ST-segment elevation and/or T-wave inversion without any coronary artery occlusion (1).
Shakespeare and Wellesbourne Lions, which organise the annual Wasperton to Stratford-upon-Avon raft race, have donated the money to the Cardiomyopathy Association.

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