Two key properties of carrier proteins
enable them to function as efficient harvesters of lower-abundance putative biomarkers in the circulation: overwhelming relative abundance and long half-lives compared with their cargo.
Total testosterone (the value measured in this study) refers to the fraction of the hormone that is bound to carrier proteins
as well as the portion that is unbound and available to tissues.
But since 99 percent of T4 is bound to carrier proteins
that carry the thyroid hormone around in your body, levels constantly change.
Several vaccination strategies have been evaluated in mouse and ferret models, including M2-expressing recombinant viruses, M2 recombinant proteins (20,21), M2-encoding plasmid DNA (29), and synthetic M2e peptides that were chemically linked to carrier proteins
or synthetically linked to defined helper T-cell determinants (22-24).
We investigated the brevetoxin congener PbTx-3 to determine its distribution among carrier proteins
, including albumin and blood lipoproteins.
DNA segments and the peptides derived therefrom are proposed to be of use directly in the preparation of vaccines and also for use as carrier proteins
in vaccine formulations.
The process is complex, involving several steps and a variety of specialized carrier proteins
and other transporter molecules to move cholesterol out of peripheral tissues and into the liver.
They also directly attack the thyroid gland and thyroid hormone carrier proteins
Products will include vaccine carrier proteins
and cell culture related growth factors.
coli doesn't waste energy making excess fat, but by cleaving fatty acids from their carrier proteins
, we're able to unlock the natural regulation and make an abundance of fatty acids that can be converted into a number of valuable products," he added.
The potential circulating forms of BNP have different intrinsic physical characteristics that can dictate antigenicity, extent of nonspecific binding during isolation, endogenous clearance kinetics, circulating half-life, and/or affinity for other proteins including cellular receptors and putative serum/plasma carrier proteins
4] circulates in the blood both freely and bound to carrier proteins