Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,903,563,191 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

ribozyme
(redirected from Catalytic RNA)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.02 sec.
ribozyme [′rīb·ə‚zīm]
(biochemistry)
A ribonucleic acid molecule that can catalyze, or lower the activation energy for, specific biochemical reactions.

Ribozyme

A ribonucleic acid (RNA) molecule that, like a protein, can catalyze specific biochemical reactions. Examples include self-splicing rRNA and RNase P, both involved in catalyzing RNA processing reactions (that is, the biochemical reactions that convert a newly synthesized RNA molecule to its mature form). Different ribozyme structures catalyze quite distinct RNA processing reactions, just as protein enzyme families that are composed of different structures catalyze different types of biochemical reactions.

Ribozymes share many similarities with protein enzymes, as assessed by two parameters that are used to describe a biological catalyst. The Michaelis-Menten constant Km relates to the affinity that the catalyst has for its substrate, and ribozymes possess Km values which are comparable to Km values of protein enzymes. The catalytic rate constant describes how efficiently a catalyst converts substrate into product. The values of this constant for ribozymes are markedly lower than those values observed for protein enzymes. Nevertheless, ribozymes accelerate the rate of chemical reaction with specific substrates by 1011 compared with the rate observed for the corresponding uncatalyzed, spontaneous reaction. Therefore, ribozymes and protein enzymes are capable of lowering to similar extents the activation energy for chemical reaction. See Enzyme, Protein, Ribonucleic acid (RNA)



Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Feedback
Mentioned in?  References in periodicals archive?   Encyclopedia browser?   Full browser?
No references found
 
00 Hardcover QP801 The 14 papers, revised to incorporate audience interaction, explore the folding pathways and mechanisms by which constituent residues interact to yield native catalytic RNA molecules and functional proteins, and how ribosomes and other macromolecular complexes self- assemble.
A technique known as in vitro selection has been used in the isolation of numerous artificial catalytic RNA molecules in various research laboratories.
Hammerhead ribozymes are small catalytic RNAs that cleave single stranded RNA substrates at specific nucleotide sequences.
 
 
 
Encyclopedia
?

Terms of Use | Privacy policy | Feedback | Advertise with Us | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.