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active site
(redirected from Catalytic domain)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
active site: see enzyme enzyme, biological catalyst. The term enzyme comes from zymosis, the Greek word for fermentation, a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists.
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active site [′ak·tiv ′sīt]
(chemistry)
The effective site at which a given heterogeneous catalytic reaction can take place. Also known as active center.
(cell and molecular biology)
The region of an enzyme molecule at which binding with the substrate occurs. Also known as binding site; catalytic site.


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The FHA domain is linked to the kinase/phosphatase catalytic domain by a flexible tether, and it exhibits a mode of target selection based on electrostatic complementarity between the binding surface and the phosphothreonine peptide.
Schering Corporation (Kenilworth, NJ) has patented a modified tumor necrosis factor-alpha converting enzyme catalytic domain, that unlike the native tumor necrosis factor-alpha converting enzyme catalytic domain, is stable at high protein concentrations.
Cysteine Residues in the Catalytic Domain of Furin are Essential for Catalytic Activity and Proper Subcellular Trafficking.
 
 
 
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