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active site
(redirected from Catalytic domain)

   Also found in: Medical, Wikipedia 0.04 sec.
active site: see enzyme enzyme, biological catalyst . The term enzyme comes from zymosis, the Greek word for fermentation , a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists.
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active site [′ak·tiv ′sīt]
(chemistry)
The effective site at which a given heterogeneous catalytic reaction can take place. Also known as active center.
(cell and molecular biology)
The region of an enzyme molecule at which binding with the substrate occurs. Also known as binding site; catalytic site.


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? Mentioned in ? References in periodicals archive
 
One of the most interesting ribozymes Bartel and his colleagues found had a catalytic domain 93 nucleotides long.
In the majority of the cases they are designed to target a specific functional and catalytic domain of the protein.
The study describes the crystal structure of VX-680 bound to the catalytic domain of BCR-ABL containing a mutation that causes Gleevec resistance but is inhibited by VX-680 in vitro.
 
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