active site

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active site:

see enzymeenzyme,
biological catalyst. The term enzyme comes from zymosis, the Greek word for fermentation, a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists.
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active site

[′ak·tiv ′sīt]
(chemistry)
The effective site at which a given heterogeneous catalytic reaction can take place. Also known as active center.
(cell and molecular biology)
The region of an enzyme molecule at which binding with the substrate occurs. Also known as binding site; catalytic site.
References in periodicals archive ?
The [alpha]-helices B and C, and the [beta] strands 3, 4, 5, 6, and 7 designated for the catalytic domain of M[F.
S5A-H, all of the 5-OH, 11-OH, and 12-OH in WEL can be exposed to the catalytic domain of the enzyme and conjugated with glucuronic acid.
In this paper, we set up a straightforward, high-throughput dHPLC-based assay to screen for the presence of mutations in the catalytic domain of ABL tyrosine kinase of 40 Turkish CML patients with imatinib resistance.
6-7 MMP-9 is secreted as zymogen with prodomain, gelatin-binding domain consisting of three contiguous fibronectin type II units, catalytic domain, proline-rich linker region, and C-terminal hemopexin-like domain.
APNs have conserved structures such as signal peptides, zinc-binding motifs, catalytic domains, N-glycosylation sites and conserved residues.
Five cysteine residues within the catalytic domain are highly conserved across species (C104, 0196, C198, C226, and 0253).
The two primers define a 470-490 bp long sequence encoding part of the TK catalytic domain [ILLUSTRATION FOR FIGURE 1 OMITTED].
One of the most interesting ribozymes Bartel and his colleagues found had a catalytic domain 93 nucleotides long.
Finally, in the catalytic domain activation loop, T229 is phosphorylated by PDK1 (3-phosphoinositide-dependent protein kinase) (Pullen et al.
In the present research, recombinant protein encoding catalytic domain of MMP-9 (MMP-9 CD) was constructed and the function of neonatal cardiac fibroblasts was investigated by cell proliferation assay, migration assay, picrosirius red assay, multiplex cytokine assay and fibroblast phenotype detection.