active site

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active site:

see enzymeenzyme,
biological catalyst. The term enzyme comes from zymosis, the Greek word for fermentation, a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists.
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active site

[′ak·tiv ′sīt]
(chemistry)
The effective site at which a given heterogeneous catalytic reaction can take place. Also known as active center.
(cell and molecular biology)
The region of an enzyme molecule at which binding with the substrate occurs. Also known as binding site; catalytic site.
References in periodicals archive ?
The recombinant catalytic domain of MMP-9, which we called MMP-9 CD, stimulated proliferation, migration, collagen synthesis and some cytokines secretion.
In this paper, we set up a straightforward, high-throughput dHPLC-based assay to screen for the presence of mutations in the catalytic domain of ABL tyrosine kinase of 40 Turkish CML patients with imatinib resistance.
The catalytic domain transfers ADP-ribose from nicotinamide adenine dinucleotide ([NAD.
Five cysteine residues within the catalytic domain are highly conserved across species (C104, 0196, C198, C226, and 0253).
As calculated by SWISSMODEL workspace, there is a catalytic domain from residues 91 to 352 in goat p70S6K; the quaternary structure is shown in Figure 2.
The Chi-a encoded a protein that included a type 3 chitin-binding domain belonging to group A and a family 18 catalytic domain belonging to subfamily A.
The catalytic domain of mammalian furin contains five cysteine residues.
Not all primer-dimers are expected to harbor catalytically active DNAzymes because this requires the primers to anneal in such a way as to copy the entire catalytic domain and a substantial portion of the hybridizing arm sequence.
The research article, entitled "Structure of the Catalytic Domain of Human Polo-like Kinase 1" was published in the May 22, 2007 issue of Biochemistry.
It also contained two conserved domains, a NAD binding domain in its N-terminal and a complete catalytic domain of sugar transport in its C-terminal.
ENB-0040 is a fusion protein that includes the catalytic domain of human tissue non-specific alkaline phosphatase (TNSALP), and a patented peptide used to target the enzyme to bone.