K-dependent toll-like receptor 9 signalling revealed in experimental arthritis.
Emerging roles of cysteine cathepsins
in disease and their potential as drug targets.
1989), and one aspartic peptidase, cathepsin
D1 <<CatDl>> (Rojo et al.
Also semi-quantifications of proteins by electrophoresis and proteolytic activities by mono-dimensional zymography for metalloproteases and cathepsins
have been reported in order to study the effect of chilling rates on the quality features of fatty livers.
Libby, "Expression of the elastolytic cathepsins
S and K in human atheroma and regulation of their production in smooth muscle cells," The Journal of Clinical Investigation, vol.
Excess intralysosomal iron-catalyzed ROS may cause LMP, whereby lysosomal cathepsins
B are released from the lysosomal lumen to the cytosol, and resultantly trigger MMP.
Results: As results, E2 and BPA upregulated the protein expression of vimentin, cathepsin
D, and MMP-2, but downregulated the protein expression of E-cadherin via ER signaling pathway, suggesting that E2 and BPA promote EMT and cell migration related gene expressions.
Key words: goatling, metabolism, myofibrillar toughness, tenderness, pH, cathepsins
In addition, LDL particles interact with proteoglycans (biglycan and decorin) and form aggregates, with a catalytic activity of sphingomyelinase, cathepsin
F and lysosomal acid lipase .
Another protein, cathepsin
B is involved in all stages of neoplastic transformation, such as tumor growth, angiogenesis, invasion and metastasis.
Cystatin C, is a small ubiquitously expressed protein found in nearly all body fluids, and is the most potent endogenous extracellular inhibitor of cysteine cathepsins
Physarolisins as well as arabidopsins are the only major intracellular enzymes, in addition to cathepsins
D and E, among the three types of peptidases studied, and elucidation of their physiological roles is awaited.