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cephalothin
(redirected from Cefalotin)

   Also found in: Medical, Wikipedia 0.02 sec.
cephalothin [′sef·ə·lə·thən]
(microbiology)
An antibiotic derived from the fungusCephalosporium,resembling penicillin units in structure and activity, and effective against many gram-positive cocci that are resistant to penicillin.


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One isolate recovered in 1998 had high-level resistance to all the drugs tested, as well as to cefalotin and fluoroquinolones (ofloxacin, ciprofloxacin, and norfloxacin); however, it was susceptible to spectinomycin, tobramycin, and gentamicin.
Minimum inhibitory concentrations (disk diffusion method) were 2 mg/L for amoxicillin, 2 mg/L for cefalotin, 0.
coli O157:H7 was resistant to amoxicillin, chloramphenicol, and cefsulodine, and sensitive to amoxicillin in combination with clavulanic acid, tetracycline, cotrimoxazole, nalidixic acid, and cefalotin.
 
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