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cell adhesion molecule
(redirected from Cell adhesion protein)

   Also found in: Wikipedia 0.01 sec.
cell adhesion molecule [¦sel ad‚hē·zhən ′mäl·ə·kyül]
(cell and molecular biology)
A class of membrane proteins comprising the outer surfaces of cell membranes in the developing nervous system that is thought to be intimately involved in guiding development during embryonic life. Abbreviated CAM.


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[Figure 1-2 ILLUSTRATION OMITTED] COMMENT Cadherins are homotypic cell adhesion proteins that have important roles in tissue morphogenesis and organ development and regulate tumorigenesis by acting as tumor suppressor genes.
Once administered, SF1126 targets specific transmembrane cell adhesion proteins known as integrins that are expressed in new tumor vasculature and within the tumor compartment.
The patent covers the use of the Company's proprietary cancer therapeutic agents to improve drug delivery to tumors by preventing a cell adhesion protein, known as occludin, from forming cellular barriers within tumors.
 
 
 
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