Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,903,287,049 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

Stem Cell
(redirected from Cell-based therapy)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.

stem cell

In living organisms, an undifferentiated cell that can produce other cells that eventually make up specialized tissues and organs. There are two major types of stem cells, embryonic and adult. Embryonic stem cells are located in the inner mass of a blastocyst (an embryo at a very early stage of development), and they eventually give rise to every cell type of the adult organism. Adult stem cells are found in some tissues in the adult body, such as the epidermis of the skin, the lining of the small intestine, and the bone marrow, where they serve in the regeneration of old or worn tissue. In cancer treatment, blood-forming adult stem cells are routinely harvested from bone marrow, stored, and then reinfused into patients to replace blood cells destroyed by chemotherapy or radiation therapy. This potential for replacing damaged tissues has aroused great interest in using embryonic stem cells to treat a number of other conditions, such as Parkinson disease, severe burns, and damage to the spinal cord. Mouse embryonic stem cells are widely used to create genetically modified mice that serve as models for investigating human disease. However, the use of human embryonic stem cells, which requires destroying the blastocysts from which they are obtained, has raised objections by those who feel blastocyst-stage embryos are human beings. The first human stem cell line was created in 1998, using cells harvested from embryos produced through in vitro fertilization. The use of human embryonic stem cells is allowed in some countries and prohibited or restricted in others.


stem cell
Histology an undifferentiated cell that gives rise to specialized cells, such as blood cells

stem cell [′stem ‚sel]
(embryology)
A formative cell.
(histology)

Stem Cell 

a cell in the continuously renewing tissues of animals that is capable of developing in different directions, within the limits of tissue differentiation.



Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Feedback
Mentioned in?  References in periodicals archive?   Encyclopedia browser?   Full browser?
No references found
 
Lead researcher Dr Valerie LeBleu, also of Harvard Medical School tested various types of cell-based therapy in mice genetically engineered to develop Alport syndrome.
Topics include: molecular control of embryonic stem cell renewal, normal and cancer stem cell niches, therapeutic potential of mesenchymal stem cell differentiation, and cancer differentiating agents in stem cell-based therapy, among others.
Our results seem to demonstrate that MSCs represent a good chance for stem cell cell-based therapy in ALS and that intraspinal injection of MSCs is safe also in the long term.
 
 
 
Encyclopedia
?

Terms of Use | Privacy policy | Feedback | Advertise with Us | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.