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cephalosporin
(redirected from Cephalosporins)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.04 sec.
cephalosporin (sĕf'əlōspôr`ĭn), any of a group of more than 20 antibiotics antibiotic, any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms.

Types of Antibiotics


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 derived from species of fungi of the genus Cephalosporium and closely related chemically to penicillin penicillin, any of a group of chemically similar substances obtained from molds of the genus Penicillium that were the first antibiotic agents to be used successfully in the treatment of bacterial infections in humans.
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. Cephalosporins, e.g., cefaclor (Ceclor), act against both gram-positive and gram-negative bacteria (see Gram's stain Gram's stain, laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls.
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) by inhibiting bacterial cell wall synthesis. They are widely used to treat gonorrhea, meningitis, and staphylococcal and streptococcal infections in patients who cannot use penicillin. Overuse of cephalosporins has led to increased bacterial resistance to the drugs (see drug resistance drug resistance, condition in which infecting bacteria can resist the destructive effects of drugs such as antibiotics and sulfa drugs . Drug resistance has become a serious public health problem, since many disease-causing bacteria are no longer susceptible to
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.)

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In three separate surveillance studies (E-0112, E-0115, E-0117) ceftobiprole was amongst the most potent cephalosporins against Enterobacteriaceae and Pseudomonas -- the most common Gram-negative bacterial pathogens associated with hospital-acquired infections -- explained in part by its enhanced affinity for the penicillin-binding protein 2 (PBP2) in pseudomonads (C1-0933).
Cephalosporins in particular seemed to provide adequate antibiotic coverage.
Cows were treated for lameness with primarily beta-lactams, cephalosporins and tetracylines.
 
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