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localized inflamation associated with tissue necrosis. Abscesses are characterized by inflamation, which is due to the accumulation of pus in the local tissues, and often painful swelling. They occur in the skin, at the root of a tooth, in the middle ear, on the eyelid (see stysty,
in medicine, acute localized infection of one or more of the glands of the eyelid, with pain, swelling, and redness of the lid margin, usually caused by a staphylococcus infection. An external sty usually releases its pus and disappears in a day or so.
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), in the mammary glands, in the recto-anal area, and elsewhere in the body. Abscesses may develop in lung tissue, in the lymph nodes, and in bone. A sinus abscess may result in a fistulafistula
, abnormal, usually ulcerous channellike formation between two internal organs or between an internal organ and the skin. It may follow a surgical procedure with improper healing, or it may be caused by injury, abscess, or infection with penetration deep enough to reach
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, and abscess of the appendix in appendicitis. Unless an abscess discharges spontaneously, surgical incision and drainage is required. See boilboil
or furuncle
, tender, painful inflammatory nodule in the skin, which becomes pustular but with a hard center (see abscess). It may be caused by any of various microbes, the most usual being Staphylococcus aureus.
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; carbunclecarbuncle,
acute inflammatory nodule of the skin caused by bacterial invasion into the hair follicles or sebaceous gland ducts. It is actually a boil, but one that has more than one focus of infection, i.e., involves several follicles or ducts.
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a localized purulent inflammation of tissues, involving their dissolution and the formation of a pus-containing cavity.

Abscesses may develop in the subcutaneous cellular tissue, in muscles, bones, and so forth, as well as in organs (such as the liver, lungs, spleen, and brain) or between them (interintestinal abscesses, subphrenic abscesses, and so on). Abscesses may appear either independently or as a complication in other diseases—for instance, pneumonia, trauma, etc. They develop as a result of the penetration of pyogenic microbes into the organism through lesions of the skin or the mucous membranes or as a result of importation of pathogenic agents from other purulent foci through the blood and lymph vessels. The microbes that have entered the tissues cause inflammation and subsequent necrosis of a section of tissue or organ. The abscess is surrounded by a zone of inflammation. The organism’s defense reaction is manifested in the formation of a capsule separating the abscess from healthy tissue. The volume of pus in the cavity of an abscess may reach several liters.

The manifestations of abscesses depend on their location, depth, and stage of development. Abscesses located close to the skin or to a mucous membrane cause their reddening, an increase in local and overall temperature, swelling, and fluctuation—a sensation of impulse transmission through a liquid from one wall to the other. When an abscess is deep, the function of the organ in which it is embedded is disturbed, body temperature rises, and pain sets in. The number of leukocytes in the blood and the erythrocyte sedimentation rate (ESR) increase. If the capsule becomes thin, the abscess will open up by itself through the skin or into the bronchial or intestinal lumen, etc. Serious complications develop when abscesses break open into the pleural or abdominal cavity. Abscesses are treated by surgery.


Rufanov, I. G. Obshchaia khirurgiia, 6th ed. Moscow, 1957. Page 311.
Davydovskii, I. V. Obshchaia patologiia cheloveka. Moscow, 1961.



A localized collection of pus surrounded by inflamed tissue.


a localized collection of pus formed as the product of inflammation and usually caused by bacteria
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As was the case in other studies, cerebral abscess in our series was the most common intracranial complication, and all 8 cases (33.
No deaths from cerebral abscess occurred in our study, nor were there any other intracranial complications.
Cerebral abscess associated with dental procedure in hereditary haemorrhagic telangiectasia.
Hoffman HJ, Hendrick EB, Hiscox JL: Cerebral abscess in early infancy.
Absence of any perifocal edema, absence of post contrast enhancement, typical CSF intensity on all CEMRI pulse sequences and CSF attenuation on NCCT rule out the possibility of cerebral abscess and brain tumors.
2] This, in turn, can result in complications such as meningitis, cerebral abscess, subarachnoid empyema, and cavemous sinus thrombosis.
Clinically and radiologically, intracranial hydatid could be confused with include arachnoid cyst, metastasis, tuberculosis, fungal infections, cerebral abscess and cystic tumors of the brain.
Tetralogy of Fallot's is the commonest congenital heart disease leads to solitary cerebral abscess.
Summers L, Mascott C, Tompkins J, Richardson D: Frontal sinus osteoma associeted with cerebral abscess formation: a case report.
12) The risk of local wound infections, meningitis, ventriculitis, or cerebral abscess are particularly high among PBI patients because of the presence of contaminated foreign objects, skin, hair, and bone fragments driven into the brain tissue along the projectile track.
Clinical and laboratory findings could also aid in the differential diagnosis of the patients with cerebral abscess formation.
We present a rare case of cerebral abscess in a chronic renal failure patient with end stage renal disease with Hepatitis C infection which is a immunocompromised condition.