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Related to Cerebral ischemia: transient ischemic attack, cerebral infarction


Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.



a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.


References in periodicals archive ?
S-nitrosylation of mixed lineage kinase 3 contributes to its activation after cerebral ischemia.
Carnosine is neuroprotective against permanent focal cerebral ischemia in mice.
Furthermore, GTPs could attenuate the increase in the expression levels of PKCa mRNA and protein caused by cerebral ischemia.
Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with symptoms of acute stroke.
Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischemia.
During surgery, in addition to the intraoperative standard monitorizationthatincluded electrocardiogram, invasive blood pressure monitoring, pulse oximetry, temperature probe and central venous pressure monitoring, bispectral index monitoring (BIS) was added for cerebral ischemia detection.
The effects of vitamin E on cerebral ischemia have been investigated in dogs, and supplementation was found to have a major protective effect.
In experimental models, increased brain temperature and cerebral ischemia produced a chain reaction, resulting in increased levels of excitotoxins and reactive oxygen species (also known as oxygen free radicals), unstable cell membranes, and an increased number of abnormal electrical depolarizations.
The coroner, Andre Rebello said Tanisha died from cerebral ischemia - lack of blood flow to the brain - a condition which affects just one in a million people.
Ninety-one pediatric stroke patients with cerebral ischemia (42 female, 49 male) and 70 control subjects (35 female, 35 male) with no familial history of a vascular disease or thrombosis were included.
Cerebral ischemia followed by reperfusion results in the production of superoxide and other ROS, as well as reactive nitrogen species.
Cerebral ischemia and subsequent reperfusion caused a substantial increase in cerebral tissue conjugated diene.