Chagas Disease

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Chagas’ Disease

 

(also called American trypanosomiasis), a transmissible parasitic disease of humans and animals caused by trypanosomes. The disease was described in 1909 in Brazil (state of Minas Gerais) by the physician C. Chagas. It occurs in Central and South America, chiefly among the poorest strata of the population, who live in dwellings infested by transmitters of the disease (bloodsucking hemipterous insects, mainly triatomids). Humans and wild and domestic animals suffering from Chagas’ disease are the sources of infection.

Infection occurs when the causative agent, together with insect feces, enters injured skin or the mucous membranes of the eyes, nose, and mouth. The main symptoms are fever and enlargement of the lymph nodes in the acute stage, with involvement of the heart and gastrointestinal tract when the disease becomes chronic. The main methods for controlling Chagas’ disease are improvement of social and living conditions of the people, disinsectization, and destruction of infected animals.

References in periodicals archive ?
La mayoria de los casos de enfermedad de Chagas por transmision congenita son asintomaticos y pueden afectar gravemente al recien nacido.
Pharmaceutical company Chemo Group reported on Thursday the receipt of approval from the first approval from the US Food and Drug Administration (FDA) for its New Drug Application (NDA) for benznidazole for the treatment of Chagas disease.
Chagas disease, or American trypanosomiasis, is a parasitic infection caused by Trypanosoma cruzi and can be transmitted through different routes, including contact with the feces of a certain insect, blood transfusions, or from a mother to her child during pregnancy.
Os estudos sobre os aspectos gastrointestinais da doenca de Chagas sao importantes por permitirem o desenvolvimento de um modelo natural para compreensao das consequencias da destruicao do sistema nervoso enterico em humanos [8].
Furthermore, a single serologic screening test reactive result confirmed as positive, though useful for blood donor management, does not define a confirmed diagnosis of Chagas disease (3).
American trypanosomiasis, also known as Chagas disease (CD), is a neglected tropical condition.
With approximately 5 to 8 million people infected worldwide, (1,3) Chagas is classified by the World Health Organization as one of the most important neglected tropical diseases.
Num contexto marcado pelo debate sobre as relacoes entre saude, desenvolvimento e produtividade do trabalho, e pelo otimismo quanto as novas "armas" para se vencer as chamadas doencas tropicais (como os inseticidas de acao residual), Dias e seus colaboradores, dentro e fora do laboratorio, foram alem das bandeiras defendidas nas decadas de 1910 e 1920 por Carlos Chagas e os partidarios do movimento medico-higienista pelo saneamento rural.
Chagas disease in the United States: a cause for concern in Louisiana?
Chagas disease - or America trypanosomiasis - is caused by the Trypansosoma cruzi parasite.
La tripanosomiasis americana, tambien llamada enfermedad de Chagas en honor a su descubridor, es una parasitosis causada por Trypanosoma cruzi, un protozoario flagelado perteneciente al orden Kinetoplastida, familia Trypanosomatidae, extensamente distribuido en el continente americano (7, 18).