Chagas Disease

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Chagas’ Disease


(also called American trypanosomiasis), a transmissible parasitic disease of humans and animals caused by trypanosomes. The disease was described in 1909 in Brazil (state of Minas Gerais) by the physician C. Chagas. It occurs in Central and South America, chiefly among the poorest strata of the population, who live in dwellings infested by transmitters of the disease (bloodsucking hemipterous insects, mainly triatomids). Humans and wild and domestic animals suffering from Chagas’ disease are the sources of infection.

Infection occurs when the causative agent, together with insect feces, enters injured skin or the mucous membranes of the eyes, nose, and mouth. The main symptoms are fever and enlargement of the lymph nodes in the acute stage, with involvement of the heart and gastrointestinal tract when the disease becomes chronic. The main methods for controlling Chagas’ disease are improvement of social and living conditions of the people, disinsectization, and destruction of infected animals.

References in periodicals archive ?
To speak with a health expert about Chagas disease, call Olive View-UCLA Medical Center at 818-364-4287.
Because dogs arriving at shelters may have high exposure to vectors, we expect that shelter dogs will provide a sensitive spatial index of Chagas disease risk across the landscape.
Chagas disease is a disease transmitted by large blood-sucking triatomine bugs commonly known as "kissing bugs.
A letter to the editor to the journal Emerging Infectious Diseases by two parasitic disease researchers charged that limited awareness of Chagas disease among US health professionals--particularly obstetricians and gynecologists--as well as the general public is hampering public health efforts to control the disease and its spread, ABC Newsletter reported.
Serologic tests are currently in use in areas where Chagas disease is endemic to detect individuals who might transmit T cruzi by transfusion.
At that time, he had a medical examination at a Catholic church because most hospitals in Japan could not make a definitive diagnosis of Chagas disease.
Transmitted by the bite of the kissing bug or vinchuca, Chagas disease is a public health problem particularly in the poor areas of Latin America and the Caribbean.
One team accomplished this by developing drugs that interfere with an enzyme found in parasites causing Chagas disease and leishmaniasis but not in humans.
Under the agreement, scientists in institutes affiliated with DNDi will test at least 150,000 compounds in the Pfizer library against Trypanosoma brucei, Leishmania donovani and Trypanosoma cruzi, the parasites that cause HAT, VL and Chagas Disease, respectively.
The IVD market research firm said that Chagas disease, Dengue fever and other diseases have not always received a lot of attention, but could see sales and new products over the next five years.
Chagas disease (infection by the protozoan Trypanosoma cruzi) is a major parasitic disease in the Americas and one of the main neglected tropical diseases.
The Bayer Cares Foundation and Caritas Argentina have laid the foundation for a new project to combat the Chagas disease in Argentina.