combinatorial chemistry

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combinatorial chemistry

[kəm‚bīn·ə¦tȯr·ē·əl ′kem·ə·strē]
(organic chemistry)
A method for reacting a small number of chemicals to produce simultaneously a very large number of compounds, called libraries, which are screened to identify useful products such as drug candidates.
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As per the firm, the NCI Chemical Biology Consortium deal will pursue to render to purchase, store, fix and distribute the present library collection.
student in the Department of Pharmacology and Chemical Biology graduate program, chronically exposed male mice over five weeks to intermittent ethanol vapor, leading to blood alcohol levels slightly higher than the legal limit for human drivers.
He is now the Mallinckrodt Professor of Chemistry and Chemical Biology at Harvard, and the Cheung Kong Visiting Professor at Peking University, Biodynamics Optical Imaging Center (BIOPIC).
Having the interface through EMBL-EBI is an even better idea, since the new SureChem interface takes advantage of EMBL-EBI's nearly 20 years' expertise in technical and professional aspects of interfacing data sets, internal analysis and customer service to the broad genomic, chemo-bioinformatic, chemical biology and drug-discovery communities.
REACTION: Joe Sweeney, Professor of Catalysis and Chemical Biology at Huddersfield University
In the Nature Chemical Biology study, Morimoto and his colleagues screened nearly one million small molecules in human tissue culture cells to identify those that restore the cell's ability to protect itself from protein damage.
Scientists hope the findings, reported in the journal Nature Chemical Biology, will lead to the development of new drugs to fight tumours.
In a recent study in the journal Carcinogenesis by the Department of Chemical Biology at the Ernest Mario School of Pharmacy, Rutgers University, stilbenes, which are phytochemicals present in grapes and berries, were shown to potentially help prevent colon cancer.
The scientists sifted through up to 23,000 different genes to find the pair linked to codeine and morphine, the journal Nature Chemical Biology reported.
One way of teaching chemical biology--using methods of chemistry to study biological phenomena--is to present in depth separate courses in chemistry, physics, and biology using standard textbooks but complementing them by lecture series, seminars, and practical courses that demonstrate the interplay between the sciences and the corresponding experimental techniques in chemical biology.
Their findings are published in scientific journals Nature Chemical Biology and Chemical Communications.
A "Journal of Chemical Biology" section in each issue carries information relevant to chemical biology research community.
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