ibuprofen

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ibuprofen

(ī`byo͞oprō'fən), nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxennaproxen
and naproxen sodium,
potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever.
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 and ketoprofenketoprofen
, nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation.
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, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967. Like other NSAIDs, it acts by inhibiting the body's production of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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. Available over the counter in a variety of preparations (e.g., Advil, Motrin, Nuprin), it is commonly used to treat rheumatoid arthritis, gout, and painful menstruation. Side effects include rash, alteration of platelet function and bleeding, and intestinal upset, which can lead to gastritis. Like other NSAIDS, it appears to have no potential for abuse or physical dependence. It should not be used by those who are allergic to aspirin.
References in periodicals archive ?
In 2003, Sabrina Johnson's parents gave her Children's Motrin to treat a fever.
The children's Motrin tablets are round, purple-colored, and scored with the letters "MO" and the number "50" on the surface.
While we are sympathetic to the pain and hardships suffered by Sabrina Johnson, Children's Motrin has been proven safe and effective for treatment of minor aches and pains and fever when used as directed, and the medicine is labeled appropriately," said Marc Boston, spokesman for McNeil Consumer Healthcare, a division of McNeil PPC.
Like many mothers and fathers would do, Sabrina Johnson's parents gave her Children's Motrin when she came home from school with a slight fever.
It's hard to remember what seeing is like, when you haven't been able to see for a long time," Sabrina Johnson testified during the trial of her family's lawsuit against Children's Motrin manufacturer Johnson & Johnson and its subsidiaries.
Last March, an FDA advisory committee of outside experts recommended that the agency approve Children's Motrin as a nonprescription medication.
During opening statements at the Malibu Courthouse on Tuesday, attorneys for Sabrina, now 11, and her parents charged that Johnson & Johnson, makers of Children's Motrin, failed to present adequate warnings on its packaging label detailing the extent of possible side effects, including Stevens-Johnson syndrome.
Jury selection has delayed the start of opening statements in a Children's Motrin product liability trial currently underway in Malibu, CA.
WHAT: Browne Greene will give his Opening Statement on Friday, June 13, 2008 at 9:00 AM in 11-year old Sabrina Brierton Johnson's Children's Motrin product liability lawsuit against Johnson & Johnson (NYSE:JNJ) at the courthouse in Malibu, CA.
Liquid Tylenol, Children's Tylenol and Children's Motrin have all seen sales dive in the high double digits.
11-Year Old Sabrina Brierton Johnson's Case is First to Be Tried against Johnson & Johnson and McNeil Consumer & Specialty Pharmaceuticals Claiming That an Allergic Reaction to Children's Motrin Caused Her Blindness
Sales of Children's Motrin soared nearly two-thirds to $23 million, helping drive category volume up 42% to $84.

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