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vinyl chloride |
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vinyl chlorideor chloroethyleneColourless, flammable, toxic gas (H2C=CHCl), belonging to the family of organic compounds of halogens. It is produced in very large quantities and used principally to make PVC, as well as in other syntheses and in adhesives. Prolonged exposure to vinyl chloride is linked to several kinds of cancer. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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2002) to chloroethylene oxide and chloracetaldehyde, metabolites that can react with DNA bases and promote mutations in bacterial and mammalian cells (Marion and Boivin-Angele 1999; Marion et al. Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans-1,2-dichloroethylene in rat. First, the form of the metric (total daily metabolism divided by the volume of the liver) was consistent with the mode of action for the end point of concern (liver tumors), which involves DNA adduct formation by a highly reactive chloroethylene epoxide produced from the metabolism of vinyl chloride. |
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