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vinyl chloride
(redirected from Chloroethylene)

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vinyl chloride

 or chloroethylene

Colourless, flammable, toxic gas (H2C=CHCl), belonging to the family of organic compounds of halogens. It is produced in very large quantities and used principally to make PVC, as well as in other syntheses and in adhesives. Prolonged exposure to vinyl chloride is linked to several kinds of cancer.

vinyl chloride [′vīn·əl ′klȯr‚īd]
(organic chemistry)
CH2:CHCl A flammable, explosive gas with an ethereal aroma; soluble in alcohol and ether, slightly soluble in water; boils at -14°C; an important monomer for polyvinyl chloride and its copolymers; used in organic synthesis and in adhesives. Also known as chloroethene; chloroethylene.


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? Mentioned in ? References in periodicals archive
 
2002) to chloroethylene oxide and chloracetaldehyde, metabolites that can react with DNA bases and promote mutations in bacterial and mammalian cells (Marion and Boivin-Angele 1999; Marion et al.
Increased risk of hepatocellular carcinoma and liver cirrhosis in ... by Martines, Diego / Environmental Health Perspectives
Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans-1,2-dichloroethylene in rat.
In silico toxicology: simulating interaction thresholds for human ... by Yang, Raymond S.H. / Environmental Health Perspectives
First, the form of the metric (total daily metabolism divided by the volume of the liver) was consistent with the mode of action for the end point of concern (liver tumors), which involves DNA adduct formation by a highly reactive chloroethylene epoxide produced from the metabolism of vinyl chloride.
A consistent approach for the application of pharmacokinetic modeling ... by Barton, Hugh A. / Environmental Health Perspectives
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