Chloroquine


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Related to Chloroquine: hydroxychloroquine, chloroquine phosphate

Chloroquine

 

a compound used in the treatment of malaria and of autoimmune and other diseases. It may be taken orally in the form of tablets or administered as a solution by intramuscular or intravenous injection.

References in periodicals archive ?
When added 1 h after infection, chloroquine at 5 [micro]g/ mL and 25 [micro]g/mL reduced the viral loads by 0.
Retinopathy is not the only consideration when taking chloroquine as systemic toxicity is also possible.
Once hailed as a wonder drug, chloroquine is still used in developing nations in the South Pacific, Africa, Asia and South America, but has been withdrawn from use in many developed countries.
Reference antimalarial compounds chloroquine and quinine were used as positive controls at concentrations recommended by WHO (2001).
While chloroquine costs a few rupees for a fourday course, the current ACTs treatment modalities cost about ` 100 or so.
In this study, chloroquine administration in a dose of 970 mg body weight of Wistar rats elevated serum hepatic and renal parameters.
While in chloroquine treated group bilirubin concentration was 1.
Clinical trials conducted by TDR (Training and research in tropical Diseases, Geneva), as early as 2003 have proved the efficacy and superiority of Artemisinin combination therapy (ACT) for chloroquine resistant malaria [7].
Researchers now have a clear path forward for undertaking projects to develop glucocorticoid and lysosomal inhibitors, and to improve the efficacy and potency of chloroquine as a therapeutic agent.
One, MrgprA3, is stimulated by chloroquine, while the second, MrgprC11, is stimulated by BAM8-22, a peptide released by immune cells, including mast cells, during inflammation.