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chlorzoxazone

   Also found in: Medical, Wikipedia 0.02 sec.
chlorzoxazone [klȯr′zäks·ə‚zōn]
(pharmacology)
C7H4ClNO2Crystals with a melting point of 191-191.5°C; soluble in aqueous solutions of alkali hydroxides and in ammonia; used as a skeletal muscle relaxant.


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Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism.
Occupational toluene exposure induces cytochrome P450 2E1 mRNA ... by Albores, Arnulfo / Environmental Health Perspectives
For example, dextromerhorphan and debrisoquine are known substrates for a particular cytochrome P450 (CYP) enzyme, CYP2D6; trimethadione, chlorzoxazone, and halothane are markers for CYP2E1 activity; morphine is predominantly processed by glucuronidation; and a host of antibiotics are not extensively metabolized but are mostly excreted unchanged by the kidneys (Bertz and Granneman 1997; Dollery 2000; Kurata et al.
Incorporating children's toxicokinetics into a risk framework by Sonawane, Babasaheb / Environmental Health Perspectives
Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C [right arrow] T mutation and rapid fractional excretion of chlorzoxazone.
The role of genetic polymorphisms in environmental health. (Research ... by Khoury, Muin J. / Environmental Health Perspectives
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