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primary biliary cirrhosis |
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primary biliary cirrhosis [¦Prīm·ə·rē ‚bil·ē·er·ē sə′rō·səs] (medicine) A slowly progressive disease primarily of middle-aged women, caused by an autoimmune destruction of bile ducts that begins as inflammation in and around larger intrahepatic bile ducts and eventually results in liver cell damage. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| 3"9 In general, cholestatic liver disease is the predominant pattern of injury seen in pediatric patients, whereas adults more commonly develop steatosis or steatohepatitis. Patients with cholestatic liver disease may develop hepatotoxic injury from endogenous bile acids, resulting in progressive hepatic damage, hepatic failure, and, ultimately, death. osteomalacia as a complication of cholestatic liver disease, which may lead to severe bone pain and multiple fractures. |
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