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primary biliary cirrhosis
(redirected from Cholestatic liver disease)

   Also found in: Medical, Wikipedia 0.01 sec.
primary biliary cirrhosis [¦Prīm·ə·rē ‚bil·ē·er·ē sə′rō·səs]
(medicine)
A slowly progressive disease primarily of middle-aged women, caused by an autoimmune destruction of bile ducts that begins as inflammation in and around larger intrahepatic bile ducts and eventually results in liver cell damage.


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SAN FRANCISCO -- The SSRI sertraline improved pruritus from cholestatic liver disease in a small double-blind crossover study of 12 patients, Dr.
Patients with cholestatic liver disease may develop hepatotoxic injury from endogenous bile acids, resulting in progressive hepatic damage, hepatic failure, and, ultimately, death.
In 1996, the product was approved for the treatment of cholestatic liver diseases including Primary Biliary Cirrhosis (PBC).
 
 
 
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