choline acetyltransferase

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choline acetyltransferase

[¦kō‚lēn ə‚sed·əl′tranz·fə‚rās]
(biochemistry)
An enzyme that transfers the acetyl group to choline in the synthesis of acetylcholine from acetyl coenzyme A and choline.
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The clinical features of Alzheimer's disease have been associated with cholinergic dysfunction due to reduction of the activity of the enzyme choline acetyl transferase.