Chorionic Gonadotropin

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chorionic gonadotropin

[‚kȯr·ē′än·ik gō‚nad·ə′trō·pən]

Chorionic Gonadotropin


a hormone produced by the villi of the chorion and the placenta in some of the higher apes and in man. It is a complex protein (glycoprotein) containing the carbohydrates galactose (10.7 percent) and hexosamine (5.2 percent) and having a molecular weight of approximately 100,000. Chorionic gonadotropin has a stimulating effect on the corpus luteum, causing it to grow in size, increasing its secretory activity and prolonging its life; it converts the corpus luteum into the corpus luteum of pregnancy, which continues to secrete the hormone progesterone until the placenta is fully formed.

Chorionic gonadotropin, while similar in effect to the luteinizing hormone of the pituitary, differs from it in certain respects: it does not restore gonads atrophied after removal of the pituitary, it has no effect on avian gonads, and it causes only a slight enlargement of the ovaries in immature rodents.

References in periodicals archive ?
Screening method to evaluate point-of-care human chorionic gonadotropin (hCG) devices for susceptibility to the hook effect by hCG E core fragment: evaluation of 11 devices.
Human chorionic gonadotropin (HCG) is a naturally occurring hormone necessary to sustain pregnancy The bishops said if the beta form of HCG is carried by a tetanus toxoid molecule and injected into a woman, it becomes an antigen that stimulates production of anti-HCG antibodies, which destroy the natural HCG.
Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy.
Human chorionic gonadotropin (hCG) is a 40kDa glycoprotein hormone secreted by the developing placenta shortly after fertilization.
The patient met all inclusionary criteria for intra-arterial interventional therapy with the exception of a positive beta human chorionic gonadotropin (hCG) at 49.
Home pregnancy tests are designed to detect the hormone human chorionic gonadotropin, or hCG, which is produced by the developing placenta that will help nourish a fetus after conception.
Human Chorionic Gonadotropin (HCG) is a naturally produced water-based hormone present in both men and women, although it is produced in great amounts in pregnant females.
For those that don't remember, in early April, Ramirez testing positive for Clomiphene and instead of serving a 100 game suspension for a second violation (remember, he tested positive in May of 2009 for hGC --human chorionic gonadotropin, a female fertility drug -- he retired).
Compared with control cells, B[a]P-primed Leydig cells in vivo produced less testosterone in response to human chorionic gonadotropin or dibutyl cAMP in vitro.
1,2) Human chorionic gonadotropin (hCG) can be detected in blood in about 12% to 33% of patients with breast carcinoma; however, many of these tumors do not show any histologic evidence of choriocarcinomatous differentiation.
Seven examples of these theoretical problems are described in the second part: parathyroid hormone, human chorionic gonadotropin, troponin, aldosterone and proteolytic renin activity, thyroglobulin, prolactin, and thyroid function tests.

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