Christian De Duve


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de Duve, Christian

(Christian Renē Maria Joseph de Duve), 1917–2013, Belgian cell biologist, b. England, M.D., Catholic Univ. of Louvain, 1941. He joined the faculty at Louvain in 1947 and at the Rockefeller Institute (now Rockefeller Univ.) in New York in 1962, splitting his time between the two institutions until he retired (1985 and 1988, respectively). He founded (1974) the International Institute of Cellular and Molecular Pathology, Brussels. In 1974 de Duve received the Nobel Prize in Physiology or Medicine with Albert ClaudeClaude, Albert
, 1899–1983, Belgian biologist, b. Longlier, M.D., Univ. of Liège, 1928. He joined the Rockefeller Institute (now Rockefeller Univ.) in 1929 and spent his entire career there.
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 and George PaladePalade, George Emil
, 1912–2008, American cell biologist, b. Iaşi, Romania, M.D. Univ. of Bucharest, 1940. He was a faculty member at the Rockefeller Institute (now Rockefeller Univ.) from 1946 to 1973, when he joined the Yale Medical School.
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 for their pioneering work on cellular structure and function, which established modern cell biology. Using differential centrifuging, a technique refined and applied by Claude, de Duve identified a new organelle, the lysosome, which contains enzymes that aid in particle digestion and promote disintegration of cells after they die. Lysosomes are critical to the body's ability to defend against bacteria, and de Duve's discovery has had important implications in medicine, as Tay-Says and a number of other hereditary diseases are caused by deficiencies in lysosomal enzymes. He wrote A Guided Tour of the Living Cell (1984) and other works.
References in periodicals archive ?
En el otro extremo, esta el Premio Nobel de Medicina 1974, Christian de Duve.
He helped discover lysosomes in 1955, visualizing the organelle that Christian de Duve had characterized only cytochemically.
Nobelists Christian De Duve and Manfred Eigen join other cellular biologists and immunologists like Sir Gustav J.
Hay que organizarse --explica la defena Ana Maria Lopez Colome (de 60 anos de edad, viuda, madre de 2 vastagos), doctora en ciencias quimicas y galardonada en abril pasado con el premio UNESCO-L'Oreal (el jurado lo presidio Christian de Duve, premio Nobel de medicina en 1974), otorgado anualmente a las 5 cientificas mas distinguidas del mundo.
Christian de Duve, a Nobel Prize winner in medicine, said, "I think the greatest threat to humanity is the excessively rapid growth of knowledge.
Among those working on the origins question is biologist and Nobel laureate Christian De Duve, who has outlined a theory of how life might have arisen.
Christian de Duve, a biochemist and Nobel Prize winner who has written on the origin of life, said Waechtershaeuser's new work was ``an extremely interesting finding which fits with the idea that life may have originated in a volcanic setting.

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