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Prophase
(redirected from Chromatin condensation)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
prophase [′prō‚fāz]
(cell and molecular biology)
The initial stage of mitotic or meiotic cell division in which chromosomes are condensed from the nuclear material and split logitudinally to form pairs.

Prophase 

one of the stages of mitotic cell division. During prophase of mitosis, the mitotic apparatus is formed and the chromosomes, which already consist of two sister chromatids, spiralize. In most cells, the nuclear membrane fragmentizes and the nucleolus is destroyed during prophase.



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However, during shorter exposure to VK2, the formation of autophagosomes was also prominent in HL60neo cells although nuclear chromatin condensations and nuclear fragments were also observed at the same time.
In a wide range of cancer cells, Curcumin has been shown to induce cell shrinkage, chromatin condensation, DNA fragmentation and block cellular signal transduction, all of which are characteristics of apoptosis.
Thus, the obvious relative decrease in the density of chromatin condensation seen in sperms of fish from polluted locations might be associated with chromosomal abnormalities, which was reported to decrease fertility potential (Abramsson, et al.
 
 
 
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