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(cell and molecular biology)
The initial stage of mitotic or meiotic cell division in which chromosomes are condensed from the nuclear material and split logitudinally to form pairs.



one of the stages of mitotic cell division. During prophase of mitosis, the mitotic apparatus is formed and the chromosomes, which already consist of two sister chromatids, spiralize. In most cells, the nuclear membrane fragmentizes and the nucleolus is destroyed during prophase.

References in periodicals archive ?
3] induced chromatin relaxation in HEK293T cells and then a return to nominal levels for the tolerated concentration, in contrast to the toxic exposure, which led to clear chromatin condensation and apoptosis.
Emphasis was laid on the effects of OA on adipogenesis, adipogenic markers, PPAR[gamma] expression and translocation, lipolysis measurements, and various apoptotic events including cell viability, apoptosis, chromatin condensation and expression of apoptotic proteins.
In conclusion, the experimental data demonstrated ischemia and reperfusion injury exerts its apoptotic effect via chromatin condensation and deceasing of viable hepatocytes.
Thus, the obvious relative decrease in the density of chromatin condensation seen in sperms of fish from polluted locations might be associated with chromosomal abnormalities, which was reported to decrease fertility potential (Abramsson, et al.
This study identified 2 stages of spermatid based oil nuclear size and chromatin condensation, but in P.
We therefore concluded that the detection of TUNEL-positive erythroblasts may reflect a normal physiologic stage of erythroid differentiation associated with chromatin condensation and subsequent enucleation.
Effect of varicocele on chromatin condensation and DNA integrity of ejaculated spermatozoa using cytochemical tests.
Apoptotic nuclei are characterized by a distinct pattern of morphological changes, including cell shrinkage, condensation, fragmentation of the nucleus, blebbing of the plasma membrane and chromatin condensation (Galluzzi et al.
BZL101 is a compound that induces apoptosis by translocating the mitochondrial transmembrane protein apoptosis inducing factor (AIF) into the nucleus of the cell, causing chromatin condensation and caspase independent DNA degradation that leads to the cell's death.
Sperm chromatin condensation is another valuable index of sperm quality that is essential for the capacity of the sperm to fertilize the ovum [19].
The structural reorganization of chromatin during nuclear condensation does not follow the same course in all insect species, and chromatin condensation was not uniform in R.