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Specific cutaneous involvement in the course of chronic myelomonocytic leukemia simultaneously with blastic leukemic transformation: Report of a case with histologic and cytochemical study, JAm Acad Dermatol 1985;12:943-948.
Chronic myelogenous leukemia Chronic myelomonocytic leukemia Mast cell leukemia Chronic monocytic leukemia Chronic neutrophilic leukemia Chronic eosinophilic leukemia
KB003, or lenzilumab, is an anti-GM-CSF mAb that KaloBios is evaluating in oncology indications where GM-CSF may play a key role, such as chronic myelomonocytic leukemia (CMML).
Following identification of infiltration of the kidney by myelomonocytic leukemia, a bone marrow aspirate and biopsy were performed, and the patient was diagnosed as having chronic myelomonocytic leukemia (CMML).
The company will discontinue its two current development programs, KB004, being studied in Phase 2 for certain hematologic malignancies, and lenzilumab, or KB003, scheduled to initiate Phase 1 development later this year in chronic myelomonocytic leukemia (CMML).
KB003, an anti-GM-CSF mAb, is being evaluated in oncology indications where GM-CSF may play a key role, such as chronic myelomonocytic leukemia (CMML).

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