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Inflammation of the pancreas.



acute or chronic inflammation of the pancreas.

Acute pancreatitis may be edematous, hemorrhagic, necrotic, or purulent. It is caused by overeating; by diseases of the stomach, duodenum, biliary tract, or liver; or by stenosis of the gland’s ducts. In acute pancreatitis the pancreas is digested by its own enzymes—trypsin, chymotrypsin, and lipase. When the gland’s tissue decomposes, kinins are released. They decrease arterial pressure and are a factor in blood circulation disorder of both organic and reflex origin in the pancreas. The kinins also cause bile to flow into the gland’s ducts, which damages their walls.

Acute pancreatitis may be marked by very severe abdominal pains, persistent vomiting, and collapse. Complications are peritonitis, abscesses, cysts of the gland, and diabetes mellitus. The disease is treated by narcotics, antibiotics, vasoconstrictors, and such antienzyme preparations as trasilol and contrical and by A. V. Vishnevskii’s paranephric novocain blockade. Serious complications are treated surgically.

In chronic pancreatitis, the gland’s external and internal secretions gradually become insufficient. The disease is treated by diet, antispasmodics, substitutes, cholegogues, antibiotics, and antienzyme preparations. During periods of remission, the patient may receive treatment at a health resort.


Shelagurov, A. A. Bolezni podzheludochnoi zhelezy. Moscow, 1970.


References in periodicals archive ?
Chronic pancreatitis occurs mainly in alcoholics and binge drinkers.
A relationship among exposure to environmental lipophilic chemicals, elevated levels of drug-metabolizing enzymes in the pancreatic exocrine and endocrine cells, and increased incidences of pancreatic cancer and chronic pancreatitis may exist in humans (Foster et al.
05: chronic pancreatitis vs carcinoma of the ampulla; chronic pancreatitis vs carcinoma of the exocrine pancreas.
Thus, vitamin A may represent a potential therapeutic strategy for chronic pancreatitis, given its ability to inhibit PSC activation and synthesis of extracellular matrix proteins.
Management of alcohol use disorders in patients with chronic pancreatitis.
Initial pathophysiological changes in chronic pancreatitis induced by pancreatic ductular obstruction model.
The results of a placebo-controlled double-blind study carried out in Japan in patients with PEI due to chronic pancreatitis or pancreatectomy showed that Lipacreon significantly improved fat absorption, an indicator used to measure nutritional status.
Three different heredity scenarios can be considered: previously established genetic syndromes, hereditary chronic pancreatitis and familial exocrine pancreatic cancer (two or more pancreatic cancer cases in first-degree relatives) [2].
They include early diagnosis, differentiating a pancreatic mass in the setting of chronic pancreatitis, and accurately staging potentially resectable pancreatic cancer with respect to the dorsal extension.
Exocrine pancreatic insufficiency (EPI) can result from various pancreatic pathologies either acquired such as chronic pancreatitis, or genetically determined such as cystic fibrosis.
On the other hand, alcohol consumption leads to liver cirrhosis in some individuals and to chronic pancreatitis in others [26].
A randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis.

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