chymosin

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chymosin

[′kī·mə·sən]
(biochemistry)
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References in periodicals archive ?
If this becomes known, he observes, "then a whole host of pharmacological agents that act on cells that produce chymase will become useful in treating EB.
Selective conversion of big endothelins to tracheal smooth muscle-constricting 31-amino acid-length endothelins by chymase from human mast cells.
The fusion protein also inhibits neutrophil elastase, mast cell chymase and tryptase, and thrombin, all of which may be involved in airway remodeling in asthma.
These mediators include histamine, tryptase, chymase, kinins, heparin, leukotrienes and PGD2.
Depletion of pre [beta]1 LpA1 and LpA4 particles by mast cell chymase reduces cholesterol efflux from macrophage foam cells induced by plasma.
SLPI also impacts mast cell chymase and tryptase, and thrombin, each of which may be involved in airway remodeling in asthma.
Published structures for Cathepsin K in NATURE STRUCTURAL BIOLOGY and chymase in BIOCHEMISTRY.
Several other tryptase inhibitors are being evaluated in preclinical studies as part of a broader inflammation program focused on developing novel therapeutics that inhibit tryptase and chymase.