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chymotrypsin
(redirected from Chymotrypsin B)

   Also found in: Medical, Wikipedia 0.01 sec.
chymotrypsin (kī'mōtrĭp`sĭn), proteolytic, or protein-digesting, enzyme enzyme, biological catalyst . The term enzyme comes from zymosis, the Greek word for fermentation , a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists.
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 active in the mammalian intestinal tract. It catalyzes the hydrolysis hydrolysis (hīdrŏl`ĭsĭs)
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 of proteins protein, any of the group of highly complex organic compounds found in all living cells and comprising the most abundant class of all biological molecules. Protein comprises approximately 50% of cellular dry weight.
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, degrading them into smaller molecules called peptides peptide, organic compound composed of amino acids linked together chemically by peptide bonds. The peptide bond always involves a single covalent link between the α-carboxyl (oxygen-bearing carbon) of one amino acid and the amino nitrogen of a second amino acid.
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. Peptides are further split into free amino acids amino acid (əmē`nō)
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. Chymotrypsin is produced in the pancreas as the inactive, or zymogen, form chymotrypsinogen. Along with other digestive enzymes of the pancreas, chymotrypsinogen is carried in the pancreatic juice pancreatic juice (păn'krēăt`ĭk, păng'–)
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 through the pancreatic duct into the duodenum. There chymotrypsinogen is activated by another enzyme, trypsin, and by molecules of active chymotrypsin. Partly because it was one of the first enzymes available commercially in crystalline form, chymotrypsin has been studied extensively.

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