Claisen rearrangement [′klā·sən ‚rē·ə′rānj·mənt]
Claisen Rearrangement
(organic chemistry)
A thermally induced sigmatrophic shift in which an allyl phenyl ether is rearranged to yield anortho-allylphenol.
Claisen Rearrangement
the migration of an allyl or substituted allyl group in allyl ethers of phenols (1) or enols (2) with the formation, respectively, of ortho-allyl phenols or C-allyl derivatives of keto-enols:
The Claisen rearrangement is widely used in organic synthesis, in particular for the synthesis of natural compounds.
The rearrangement was discovered by the German chemist L. Claisen in 1912.
REFERENCE
Organicheskie reaktsii, collection 2. Moscow, 1950. Pages 1–60. (Translated from English.)Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
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