clathrin


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clathrin

[′klath·rən]
(cell and molecular biology)
A protein that forms a lattice-shaped coating, through the assembly of subunits called triskelions, on the cytosolic side of membrane regions called coated pits during the initial stages of receptor-mediated endocytosis. Invagination of the pit results in a clathrin-coated vesicle.
References in periodicals archive ?
Light-driven shedding is mediated by arrestin and clathrin (Sacunas et al.
Furthermore, the accumulation of phosphorylated a-synuclein was observed in neuronal cell bodies in an AP-2 (a clathrin adaptor protein) subunit knockdown, mimicking synucleinopathy ([alpha]-synuclein-mediated neurodegenerative disorder).
SNP Top BLASTx hit Accession 35,850 Clathrin heavy chain [Penaeus monodon] AJM87267.
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
The constitutively expressed gene clathrin adapter complex (CAC) was used as a positive control (Exposito-Rodriguez et al.
lt;B A Clathrin Cage which takes takes molecules around in a cell Maria Voigt
The complex now enables clathrin to associate with the receptor and to build a clathrin coated pit in which the receptor is internalized via endocytosis (Claing et al.
Contrarily, CD1a does not interact with AP-2 and is internalized using clathrin and dynamin-independent pathways [34].
Schein came to the cagelike molecules because he was curious about clathrin, a protein that assembles itself in cages.
Clathrin is involved in moving resources inside and outside cells, and in that process it forms only a handful number of shapes.
It constitutively cycles through clathrin vesicles and recycling endosomes in a pathway that is not dependent on cAMP signaling in endothelial cells.
Clathrin coat is needed for invagination of the cell membrane.

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