Clemmensen Reaction
the substitution of an oxygen atom in an aldehyde or ketone group by two hydrogen atoms during interaction with amalgamated zinc and hydrochloric acid:
The Clemmensen reaction is used in laboratory organic synthesis predominantly for the preparation of fatty-aromatic hydrocarbons by the reduction of corresponding ketones. For example, an 80–percent yield of ethylbenzene is obtained from acetophenone.
The reaction was developed by the American chemist E. C. Clemmensen in 1913–14.
REFERENCE
Organicheskie reaktsii, collection 1. Moscow, 1948. Pages 194–266. (Translated from English).Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
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