Clonorchiasis


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Related to Clonorchiasis: schistosomiasis, opisthorchiasis

clonorchiasis

[‚klōn·ȯr′kī·ə·səs]
(medicine)
A parasitic infection of humans and other fish-eating mammals which is caused by the trematode Opisthorchis (Clonorchis) sinensis, which is usually found in the bile ducts.

Clonorchiasis

 

a helminthic disease of man, cats, dogs, and certain other mammals caused by the flatworm Clonorchis sinensis, which infests the bile ducts, gallbladder, and pancreatic ducts.

Chlonorchiasis is widespread in China, Japan, Korea, and, in the USSR, the Far East. The source of infection is an individual affected with the parasite; animals are of secondary importance as a source. The eggs of the flukes, excreted with the feces and reaching a body of water, are taken up by mollusks (Bithynia bongicornis and others). The helminth develops within the mollusk until it reaches the cercaria stage. The cercaria emerge and penetrate carp (and, possibly, certain crustaceans), within which they change into metacercaria. Human beings and animals become infected when they eat raw, inadequately cooked, or inadequately salted fish. A fever develops two to four weeks after a person becomes infected, the number of eosinophils in the blood increases, and the liver (and sometimes the spleen) become enlarged. Several weeks later these symptoms subside and the disease becomes chronic with brief, intermittent exacerbations. Clonorchiasis causes functional disturbances (dyskinesia) of the biliary tract, hepatitis, pancreatitis, and, sometimes, cirrhosis of the liver. Diagnosis is based on the detection of the fluke eggs in the feces or duodenal contents. A specific agent, chloxylum, as well as cholagogic and antispasmodic agents, are used in treatment, and the biliary tract should be drained. Chlonorchiasis can be prevented by keeping lakes and streams free of pollution by feces and by cooking fish properly (boiling, thorough frying, hot smoking, pickling for two or three weeks).

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References in periodicals archive ?
In surveys 1-3, clonorchiasis prevalence in different age groups was significantly correlated with the corresponding infection intensity in terms of the geometric mean number of EPG after logarithmic transformation (p<0.
Analysis of data from 3 parasitic disease surveys con ducted in Hengxian County over the last 22 years showed substantial decreases in the trend of STHs prevalence and substantial increases in the patterns of clonorchiasis prevalence and infection intensity.
Clonorchiasis is a neglected parasitic disease in China: no nationwide intervention or control programs have been implemented to reduce the caseload (12).
These developments are of considerable health concern because fish and crustaceans act as second intermediate hosts of clonorchiasis and paragonimiasis, respectively.
Clonorchiasis in the upper Amur region: biology, epidemiology, clinical presentation (in Russian).
Clonorchiasis Worms reproduce in gastropod snails, then are swallowed by freshwater fish or other snails.
Source: WHO 1996 (205) except amoebic dysentery, bacillary dysentery dracunculiasis, dengue and RVF from WHO 1998 (200); and clonorchiasis and paragonimiasis from Muller & Morera 1994 (119).