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coagulation
(redirected from Clotting factors)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
coagulation (kōăg'ylā`shən), the collecting into a mass of minute particles of a solid dispersed throughout a liquid (a sol), usually followed by the precipitation or separation of the solid mass from the liquid. The casein in milk is coagulated (curdled) by the addition of acetic acid or citric acid. The albumin in egg white is coagulated by heating. The clotting of blood is another example of coagulation. Coagulation usually involves a chemical reaction. Lyophobic particles (see colloid colloid (kŏl`oid) [Gr.,=gluelike], a mixture in which one substance is divided into minute particles (called colloidal particles) and
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) lose their electric charge by reacting with oppositely charged particles. Lyophilic particles undergo a reaction that causes them to lose their solubility. In either case coagulation occurs. The formation of a gel by evaporation or cooling of a sol is usually called gelation rather than coagulation.

coagulation

Process of forming a blood clot to prevent blood loss from a ruptured vessel. A damaged blood vessel stimulates activation of clotting factors, eventually leading to the formation of long, sticky threads of fibrin. These make a mesh that traps platelets, blood cells, and plasma. This meshwork soon contracts into a resilient clot that can withstand the friction of blood flow. Under abnormal circumstances, clots can form in an intact vessel and may block it. See also anticoagulant.


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Consider the intense demand for plasma, the clear liquid portion of blood that contains therapeutic molecules such as clotting factors and albumin, a protein regularly used to treat shock and other conditions.
concluded that the imbalance of clotting factors and other blood proteins induced by marathon running may trigger a cardiac event.
 
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