cofactor

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cofactor

[′kō‚fak·tər]
(biochemistry)
A specific substance required for the activity of an enzyme, such as a coenzyme or metal ion.
(mathematics)
References in periodicals archive ?
dimethyl aniline was mixed with 2 ml of co-factor and incubated for 5 min at 37degC.
Selenium: A vital co-factor for glutathione, the body's premier antioxidant, selenium also confers protection against infections.
alpha]-Lipoic acid is an endogenous thiol and co-factor of [alpha]-dehydrogenase complexes that are reduced to dihydrolipoic acid (DHLA; a potent antioxidant against all major oxy radical species) following dietary supplementation; DHLA is an important agent in recycling vitamin C during oxidative stress and can be an effective glutathione substitute (69).
Without further exploration, one might have concluded that high vascular pressure was the essential VILI co-factor, but as later experiments indicate, it is the gradient of vascular pressure--a correlate of cardiac output and flow--that is most important.
While HIV/AIDS is predominantly spreading through sexual intercourse, this biological co-factor induced by malaria has contributed considerably to the spread of HIV by increasing HIV transmission probability per sexual act," said Abu-Raddad, an HIV/AIDS research scientist in the Hutchinson Center's Statistical Center for HIV/AIDS Research and Prevention and the Center for Studies in Demography and Ecology at the University of Washington.
When the co-factor epithiospecifier protein (ESP) is present, an inactive hydrolysis product--sulforaphane nitrile (SFN)--forms at the expense of SF.
Co-factor contributions vary by cultivar, by harvest conditions and undoubtedly by viticultural practices.
In addition, mouse studies have already resulted in some discoveries about HIV, including the identification of co-receptors, cyclin T1 (a necessary co-factor for Tat and TAR during transcriptional elongation), and host factors required for viral assembly and release.
Vitamin B12 is a required co-factor for this enzyme but for some reason in the so-called vitamin B12-responsive forms of MMA there is insufficient co-factor available to the enzyme.
The patented NMR Solve approach allows Triad to focus on the relevant binding domains by studying the protein while a co-factor probe is bound.
Infection with other STDs is an important co-factor for transmission of HIV; genital ulcer diseases in particular, such as chancroid, provide an entry point for HIV.