coeliac disease

(redirected from Coeliac sprue)
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coeliac disease

a chronic intestinal disorder of young children caused by sensitivity to the protein gliadin contained in the gluten of cereals, characterized by distention of the abdomen and frothy and pale foul-smelling stools
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The association between coeliac sprue and malignant lymphoma was described in 1937 [29].
Coeliac disease (CD), also known as Coeliac sprue, nontropical sprue, gluten-induced enteropathy, or gluten-sensitive enteropathy (GSE) is a chronic, systemic, autoimmune disorder predominantly affecting the small intestine, and caused by the hypersensitivity to certain ingredients in wheat (gluten), rye (secalins), and barley (hordeins), in genetically susceptible individuals.
Studies of intestinal lymphoid tissue, XII: epithelial lymphocyte and mucosal responses to rectal gluten challenge in coeliac sprue.