collagenase

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Related to Collagenases: Interstitial collagenase

collagenase

[′kä·lə·jə‚nās]
(biochemistry)
Any proteinase that decomposes collagen and gelatin.
References in periodicals archive ?
NCI, a database of ligands where the chemical structure of the drug collagenase is drawn in editor page and the data is transferred to query page.
Collagenase is the drug which binds on the collagen receptor.
The chemical structure of the Collagenase drug is retrieved from the NCBI PubChem compound.
The interacting amino acid of Collagen receptor, when the analog of Collagenase drug is docked, was glycine, proline and hydroxyproline.
In the present study, the analogs of Collagenase drug had a positive role in the process of wound healing.
These amino acids are potentially active in triple helical structure of collagen receptor for collagenase ligand.
The analogs of collagenase drug acts on the amino acids such as proline and hydroxyproline to inhibit their role in the triple helical structure of collagen protein and to release fibrin or fibronectin which prevents blood loss in wound.
It is finally concluded that in the five analogs of collagenase drug the most effective analogs which are acting on the Proline-6 and Hydroxyproline -7 are responsible for forming the triple helical structure of the collagen protein.
Injectable collagenase clostridium histolyticum for Dupuytren's contracture (CORD I).
Injectable Collagenase Clostridium Histolyticum: A New Nonsurgical Treatment for Dupuytren's Contracture.
A one-step sandwich enzyme immunoassay for inactive precursor and complexed forms of human matrix metalloproteinase 9 (92 kDa gelatinase/type IV collagenase, gelatinase B) using monoclonal antibodies.
Studies on the interaction between heparin and mouse bone collagenase.