a) Positive control as known competitive inhibitor
The first property is that an uncompetitive inhibitor as a target conjugate is preferred over a competitive inhibitor
because uncompetitive inhibitors are rare in nature and should be less susceptible to interferences from drugs and naturally occurring substances, which frequently are competitive inhibitors
It's a very straightforward competitive inhibitor
of the enzyme,' Goldman says.
The coactivator and growth promoting functions of AKR1C3 were inhibited by a novel AKR1C3-selective, competitive inhibitor
developed by GTx.
Enzyme kinetic studies showed that the MA was not only a competitive inhibitor
of CYP3A4 in humans, but also a competitive inhibitor
of CYP2C11 and 3A2 in rats, with [K.
Carnosine has been shown to act as a competitive inhibitor
of the non-enzymatic glycosylation of proteins," Babizhayev and colleague A.
Perchlorate is a competitive inhibitor
of the sodium iodide symporter, the thyroid cell-surface protein responsible for transporting iodide from the plasma into the thyroid.
Alpha methyl ornithine, a potent competitive inhibitor
of ornithine decarboxylase blocks proliferation of rat hepatoma cells in culture.