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complementation group

   Also found in: Acronyms 0.01 sec.
complementation group [‚käm·plə·mən′tā·shən ‚grüp]
(genetics)
Different mutations in the same cistron or gene.


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Previous research has firmly established that four genetic pathways, known as Complementation Groups A, B, C and D work together to prevent cell immortality.
1997) had shown that MMC-induced apoptosis in FA complementation group C (FA-C) cells occurred under normoxic conditions (associated with redox-cycling mechanisms), whereas MMC was ineffective in causing apoptosis under hypoxic conditions (with prevailing cross-link formation).
 
 
 
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