confocal microscope

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Related to Confocal microscopy: fluorescence microscopy

confocal microscope

[¦kän‚fō·kəl ′mī·krə‚skōp]
(biophysics)
A microscope that creates high-resolution images of very small objects by using a condenser lens to focus the illuminating light from a point source into a very small diffraction-limited spot within the specimen, and an objective lens to focus the light emitted from that spot onto a small pinhole in an opaque screen.
References in periodicals archive ?
In comparison, scanning techniques such as confocal microscopy expose every pixel only for a few microseconds with much higher laser power, which may cause fluorophore saturation.
vivo confocal microscopy of the cornea has been developed, mainly for use in patients with diabetic neuropathy.
Reflectance confocal microscopy is another high-resolution imaging technique that is just beginning to be explored for oral cancer detection.
This makes it ideal as an entry-level system for confocal microscopy.
These confocal microscopy images of the metallic coil coating without cellulose acetate butyrate (Figure 1) show a multitude of high peaks, indicating a rough surface.
394") stroke length and 12 mm optics mount, the LFA is marketed for: Optical focusing, scanning, inter-ferometry, surface structure analysis, disk drive testing, autofocus systems, confocal microscopy, biotechnology, and semiconductor test equipment.
Using a new application of a form of imaging called multiphoton confocal microscopy, the researchers created snapshots of selected areas of the brain on a daily basis and made a record of plaque formation over time.
Phagosome formation and localization of signaling proteins were studied by immunostaining with fluorescent antibodies followed by confocal microscopy.
In the present study, the 3-D arrangement of vessels in mature intermediate and terminal placental villi was examined using the combination of confocal microscopy and image processing.
Confocal microscopy results showing improved fluorescence imaging (red fluorescence for Eu, green fluorescence for Tb, and no autofluorescence for controls) suggest that this technique might be used for live-cell imaging, a requisite analytical tool in most cell biology experiments and a routine procedure in neurobiology, developmental biology, pharmacology, and several other related biomedical research fields.