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congenital disorder |
Also found in: Wikipedia | 0.59 sec. |
congenital disorderA large group of disorders arising during development that cause abnormality of the human body. Most are due to genetic factors such as inherited or spontaneous mutations, whereas others are caused by environmental influences during pregnancy such as exposure to harmful chemicals. The most severe and lethal disorders arise during the first 28 days of development and include gross brain anomalies and heart defects. The mildest malformations occur in the late stages of development and are often the result of dominant inheritance, whereas complex congenital syndromes are often the result of recessive inheritance. See also birth defect; Down syndrome. |
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? Mentioned in | ? References in periodicals archive | ||
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| Older theories hold that they are congenital abnormalities caused by an incomplete obliteration of pharyngeal pouches. To assess the association between cesarean delivery and stillbirth in subsequent pregnancy, the researchers examined the records of women who had had two consecutive singleton births at 20 or more weeks of gestation; infants with congenital abnormalities were excluded. The EUROHAZ-CON study of hazardous waste landfill sites in five European countries found a 33% increase in the risk of congenital abnormalities in infants born to mothers living within 3 km of the sites (Dolk et al. |
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Congenital abnormalities
