As shown in figure 2, this creates a conjugated system
via the two aromatic rings, known as a quinone imide.
This is due to the much larger molecule number density in the solid film than that in the solution, especially to the much larger delocalized [pi]-electrons conjugated system
formed in the film.
The effect of extending the conjugated system
by means of fusing a large aromatic structure to the 4- and 5- positions of the oxazole ring has not been considered.
Knopov has extensive knowledge of Chemistry, Manufacturing and Control, or CMC, development for various technology platforms including commercial production of enzymes, small anticancer liposomal products as well as advanced delivery systems for antisense, plasmids and siRNA based on lipids, polymer nanoparticles and conjugated systems
Although he continues his interest in unusual conjugated systems
, his major emphasis in recent years has been on the synthesis and study of molecules that imitate enzymatic reactions.