Still other researchers, including Harry Dorn and his coworkers at Virginia Tech in Blacksburg, are putting four atoms inside fullerene cages to create multiple-use contrast agents
Used most commonly today to better delineate endocardial borders, contrast agent
potential has been significantly expanded with the introduction of Real-time Perfusion Imaging.
However, recent studies have discovered harmful side effects, such as nephrogenic systemic fibrosis, stemming from the use of this contrast agent
in some patients, forcing the Food and Drug Administration (FDA) to place restrictions on the clinical use of gadolinium.
If the synthetic HDL works as well in people, Cormode says, the new contrast agent
will improve physicians' ability to track the effectiveness of plaque-busting treatments.
Although it is less common to use negative contrast agents
such as milk or VoLumen, they may be particularly useful in patients with inflammatory bowel disease or infiltrating cancers where it is important to enhance the view of the bowel wall, Dr.
The FDA has approved five gadolinium-containing contrast agents
for use during MR procedures, but not for MRA.
Novel solutions for in vivo microscopic imaging systems or microscopic implanted devices with high spatial and/or temporal resolution that may use either intrinsic or exogenous contrast agents
a 277-bed acute care community hospital, increased costs related to the use of new low-osmolar contrast agents
have been estimated to be at least $600,000 per year.
New studies reflecting use in more than 5 million patients show that ultrasound contrast agents
present an extremely small risk to patients while improving the accuracy of ultrasound diagnoses and, in many cases, avoiding the need for risky and expensive downstream testing, Dr.
The use of gadolinium-based MRI contrast agents
has been limited by safety concerns; however, the use of more stabilized and safer MRI contrast agent
alternatives will support future growth.
Large unmet medical need for ultrasound contrast agents
If approved, Vasovist will establish a new class of blood pool contrast agents
for magnetic resonance angiography (MRA) to diagnose vascular disease.