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Coronaviridae

   Also found in: Medical, Wikipedia 0.01 sec.
Coronaviridae [kə‚rō·nə′vī·rə‚dē]
(virology)
A family of vertebrate viruses consisting of the single genus Coronavirus; the prototype, avian infectious virus, has an enveloped spherical form with large spikes and a helical nucleocapsid with single-stranded ribonucleic acid.


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MHV is a member of the coronavirus family, Coronaviridae, which includes the virus that causes severe acute respiratory syndrome (SARS), as well as many viruses associated with the common cold.
This feature is typical of all Coronaviridae viruses that bud intracellularly at membranes of the intermediate compartment between the endoplasmic reticulum and the Golgi complex, whereas newly assembled virions reach the cell surface by vesicular transport (16).
A virus was isolated from the oropharynx of a SARS patient and identified by morphologic characteristics as belonging to the family Coronaviridae (6-8); however, coronaviruses had not been a prime consideration in the differential diagnosis since they rarely cause lower respiratory tract infections in humans (9-11).
 
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