corticotropin-releasing hormone

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corticotropin-releasing hormone

[‚kȯrd·ə·kō′trō·pən ri¦lēs·iŋ ‚hȯr‚mōn]
(biochemistry)
A substance produced by the hypothalamus that stimulates the pituitary gland to produce adrenocorticotropic hormone (ACTH). Abbreviated CRH.
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Structure of class B GPCR corticotropin-releasing factor receptor 1, 2013, Nature.
Effects of third intracerebroventricular injections of corticotropin-releasing factor (CRF) on ethanol drinking and food intake.
Role of corticotropin-releasing factor in drug addiction: potential for pharmacological intervention.
Hypophysial-portal plasma levels, median eminence content, and immunohistochemical staining of corticotropin-releasing factor, arginine vasopressin, and oxytocin after pharmacological adrenalectomy.
Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats.
Keywords: Essential oil; Atractylodes lancea; Restraint stress; Gastric emptying; Gastrointestinal hormone; Corticotropin-releasing factor
Corticotropin-releasing factor (CRF) has been reported to be elevated in the cerebrospinal fluid of depressed patients, Dr.
and his colleagues turned their attention to a gene called type I corticotropin-releasing factor receptor (CRFR1), because it's widely involved in the brain's responses to stress.
There is also very elegant and interesting basic science work and supportive preliminary clinical data suggesting that corticotropin-releasing factor antagonists might offer benefits to patients with IBS and diarrhea.
Hydrogen sulfide also affects the hypothalamic pituitary adrenal axis and the corticotropin-releasing factor in animal studies, the report said.
Two neurochemical systems that we have determined to play a critical role are corticotropin-releasing factor (CRF) and noradrenaline (NE).

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