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warfarin
(redirected from Coumadin)

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warfarin (wôr`fərĭn), anticoagulant anticoagulant , any of several substances that inhibit blood clot formation (see blood clotting). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance,
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 used to treat blood clots. In large doses it causes bleeding. Warfarin, mixed with bait, is used in rodent control.

warfarin

Anticoagulant drug, marketed as Coumadin. Originally developed to treat thromboembolism (see thrombosis), it interferes with the liver's metabolism of vitamin K, leading to production of defective coagulation factors. Warfarin therapy risks uncontrollable hemorrhage, either spontaneously or from any cut or bruise; it requires frequent checks to maintain the proper level in the blood. In high concentrations, warfarin is used as a rodent poison, causing death by internal bleeding.



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People who take Coumadin because of atrial fibrillation include active and otherwise healthy people, as well as elderly people for whom the drug may be contraindicated," said Dr.
However, since she was on Coumadin (warfarin sodium blood thinner) surgery had to be delayed for five days while the Coumadin was discontinued.
 
 
 
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