Coumarin

(redirected from Coumarins)
Also found in: Dictionary, Medical, Wikipedia.
Related to Coumarins: Tannins, Flavonoids

coumarin

[′kü·mə·rən]
(organic chemistry)
C9H6O2 The anhydride of o-coumaric acid; a toxic, white, crystalline lactone found in many plants and made synthetically; used in making perfume and soap. Also known as 1,2-benzopyrone.

Coumarin

 

a lactone of o-coumarinic acid; colorless crystals with an odor of new-mown hay. Melting point, 70°C; boiling point, 291°C. It has the following structural formula:

Coumarin is readily soluble in alcohol and ether and poorly soluble in water. It occurs in glucoside form in many plant species, for example, in sweet clover and sweet grass. Coumarin is industrially prepared from salicylic aldehyde and acetic anhydride. It serves as an odor-enhancing substance in the tobacco and perfume industries.

References in periodicals archive ?
Chemical constituents of Murraya siamensis: Three coumarins and their anti-tumor promoting effect.
Seven coumarins (coumarin, coumarin-3-carboxylic acid, ellagic acid, esculetin, 4hydroxycoumarin, scopoletin, and umbelliferone) were purchased from Sigma-Aldrich (St.
Then, epoxypropoxy coumarin (EPC) was conjugated to hydrophobically modified poly (vinyl alcohol)--epoxypropoxy coumarin conjugate (HmPVA) by the reaction between the epoxy groups of EPC and the hydroxyl group of HmPVA (Fig.
Warfarin's monopoly on oral anticoagulation therapy, as well as that of other vitamin K antagonists derived from coumarin, is over.
Ruta species are sources of diverse classes of natural products such as flavonoids, alkaloids, essential oils, coumarins, phenols, saponins lignans, and triterpenes, with biological activities including antifungal, antioxidant, phytotoxic, abortive, depressant, antidotal and anti-inflammatory (Mohhr, 1982; Juan, 1984; Raghav et al, 2006; Kuzovkina et al.
Strawberries are rich in coumarins - which prevent the formation of cancer-causing nitrosamines in the body - vitamin C and phenols, which have strong antioxidant properties.
Coumarins, which are a precursor of some anticoagulants.
PC contains coumarins, flavonoids, and merotepenes such as psoralen, isopsoralen, neobavaislfoavone, bovachin, bavaislfoavone, bavachromene, psoralidin, corylifolinin, bavachinin, bavachalcone.
The inhibition of conjugated diene formation may be related to hydroperoxide interacting polyphenol compounds like flavones, coumarins, chalcones and cinnamic acids which may neutralise hydroperoxides by the reduction process (Tiwari 2004).
According to Naturex, Fraxinus excelsior has been reported to contain primarily coumarins, secoiridoids and phenylethanoids.
17,18) Like their chemical cousin warfarin (Coumadin[R]), coumarins inhibit platelet aggregation, and may thus help prevent blood clots.