Creutzfeldt-Jakob disease

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Related to Creutzfeld-Jakob disease: Huntington's disease, mad cow disease

Creutzfeldt-Jakob disease:

see prionprion
, abnormal form of a protein found in mammals, believed to cause a group of diseases known as prion diseases or transmissible spongiform encephalopathies. Well-known prion diseases are Creutzfeldt-Jakob disease (CJD) and kuru in humans, scrapie in sheep, bovine
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The Government announced last month that experts had advised a ban on blood donation on anyone who had had a transfusion since January 1980 because of a 'slight risk' of the transmission of variant Creutzfeld-Jakob disease (vCJD).
It follows medical research which showed a 'slight risk' of the transmission of variant Creutzfeld-Jakob disease (vCJD).
Finally, some experts would like to see testing with prions, a type of protein that can become "misfolded" and contribute to brain diseases including variant Creutzfeld-Jakob disease and kuru, a fatal dementia among a tribe in New Guinea caused by eating the remains of diseased humans.
There are some doubts in the medical world about the link between socalled mad cow disease and new variant Creutzfeld-Jakob Disease (nvCJD) where rates of new cases has remained fewer than 25 a year.
Beginning next spring, thousands of additional people who have lived in or visited Europe will be barred from donating blood as a new precaution against the spread of variant Creutzfeld-Jakob disease (vCJD), the human form of mad cow disease that apparently is spread by eating infected beef.
The term "vCJD" refers to variant Creutzfeld-Jakob Disease (sometimes also called "new variant CJD" or "nvCJD"), a form of the disease that scientists have shown is caused by exposure to mad cow disease.
Since the HIV epidemic, the possible but as yet unproven transmission of new variant Creutzfeld-Jakob disease (nvCJD) by transfusion in humans represents yet another major threat to the safety and availability of our blood supply.
Originally discovered in Britain in 1996, BSE has been linked to the fatal human illness variant Creutzfeld-Jakob disease (vCJD).
Prion diseases became a worldwide concern in the mid-1980s with the outbreak of BSE or "Mad Cow Disease" in cattle in the United Kingdom and the subsequent identification in 1996 of a new variant of Creutzfeld-Jakob disease (nvCJD) in humans.
The safety of bovine collagen products is being questioned following the problem of "mad cow illness" and possible transmission of Creutzfeld-Jakob disease to humans.
In an abstract presented at the XXV International Congress of the World Federation of Hemophilia (WFH) in Seville, Spain, Bayer BP scientists shared data showing the prion protein that causes variant Creutzfeld-Jakob Disease (vCJD) can be removed by purification processes used in the manufacture of blood protein products, reducing the theoretical risk of transmission through use of these products.