Crohn's disease

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Related to Crohn: Morbus Crohn

Crohn's disease:

see colitiscolitis,
inflammation of the colon, or large intestine. The term "colitis" may be used to refer to any of a number of disorders involving the colon. Symptoms include diarrhea (often with blood and mucus), abdominal pain, and fever.
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Crohn's disease

[′krōnz diz‚ēz]
(medicine)
Chronic inflammation of the colon and stomach of unknown etiology that involves the full thickness of the intestinal wall, often with bowel narrowing and obstruction of the lumen. It is usually accompanied by granulomas; and abdominal cramps, alteration of bowel function, and diminished food intake are common.
References in periodicals archive ?
Immunologist Bill Paxton, who worked with Crohn at the Aaron Diamond AIDS Research Centre in New York, told SHOTS: "Steve was quite phenomenal.
An artist and editor, Crohn committed suicide in August.
12,18,20) Although Crohn disease typically affects the terminal ileum more often than the large bowel, cutaneous manifestations of Crohn disease appear to occur more often in patients who have involvement of the colon.
Metastatic Crohn disease presents microscopically as sterile, noncaseating granulomatous inflammation located primarily in the superficial papillary and deep reticular dermis with occasional extension into the subcuticular fat (Figures 2 through 5).
Thrombophilia in Crohn disease is probably due to inappropriate hemostasis with a hypercoagulable state, thrombocytosis, hyperfibrinogenemia, hyperhomocysteinemia and increased levels of lipoproteins, which probably play a role in local microcirculatory alterations leading to CD itself.
Successful treatment of severe gastrointestinal bleeding secondary to Crohn disease with recombinant factor VIIa.
Crohn learned about Delta 32 after he was enrolled in a 1994 Aaron Diamond AIDS Research Center study of a dozen HIV-exposed individuals who remained seronegative over long periods of time.
Crohn himself has long relied not on his theoretical immunity to avoid infection but on safer sex.
Coverage of the Crohns Disease pipeline on the basis of therapeutic class, route of administration and molecule type.
The authors have estimated the global Crohns disease therapeutics market to be valued at $2.